This study aims to analyze the effect of work environment, compensation and religiosity on turnover intention of Islamic Banking employees in Indonesia. The questionnaire was filled out by 209 employees of Islamic banks in Indonesia and the data obtained was processed using Structural Equation Modeling (SEM) method with SmartPLS software version 3.2. Work environment and compensation negatively affect turnover intention. Religiosity is the only variable that posit ively influences turnover intention. This paper is one of the pioneer research in the field of Human Resource Development (HRD) focusing on the matter of turnover intention which combining three independent variables (work environment, compensation and religiosity) with at least 50% Islamic Banks in Indonesia took place as samples. This research is expected to benefitting management in Islamic banking so they could establish proper strategic policy in the field of employment, especially those related to turnover intention to control employee turnover rate in order to improve the performance of Islamic banking in Indonesia in the future.