Religious is an essential factor to be studied because it is one of the most universal social institution and influence, it has a great influence on people's attitude, values and behavior at the individual and society. Religion also affect human attitude towards the various activities of daily life as well as in economics. Many studied show that religious values of human beings directly or indirectly will affect the choice of action or human economic behaviour. Therefore, religion has significant influence in economic life. In conventional perspective, the influence of religion seen in human economic behavior, as well as in Islamic economics view. Behavior in economic theory based on assumptions of rationality that adopted by economic modern today. The theory of rational economic man embraced the concept of self-interest and materialism which denies the existence of religious values and ethics in the economic area. Thus, in this context this paper intend to investigate and find the answer on how Islam (Qur’an) envisage human economic behaviour?. This paper also demonstrates and confirms the Islamic principle of human economics behaviour from the source divine Al-quran and hadist as evidence the influence of religious values in the economic life of Islam.